In the year 2220 A.D., the Earth Federation launches a plan to evacuate Earth when discovering that a traveling black hole capable of destroying anything in its path is on course towards the solar system. As the people on Earth prepare to relocate to planet Amare, whose ruler offers refuge, the tyrants known as the "S.U.S. Empire" attack the first Earth evacuation fleet. After learning that his wife Capt. Yuki Mori-Kodai disappeared in the battle and that legendary space battleship Yamato has been fully rebuilt, Susumu Kodai accepts command of the ship as he intends to not only help humanity once again, but also find Yuki in the hope of helping his relationship with his daughter Miyuki, who puts the blame on him for her mother's disappearance. But in order to fullfil the mission, the Yamato must go through battles against the SUS Empire, who intend to spoil humanity's hopes of finding a new place to live in and turn Earth into energy for their own selfish needs.

A watery world called Aquarius that is destined to destroy all of the planet Earth. Can the great Yamato stop this devastation? Final Yamato (宇宙戦艦ヤマト・完結編 Uchuu Senkan Yamato Kanketsu Hen, lit. "Space Battleship Yamato: Final Saga") is a 1983 Japanese anime science fiction film and the fourth theatrical movie of the Space Battleship Yamato saga (known as Star Blazers in the United States). The 70mm print had a running time of 163 minutes, making Final Yamato the longest running animated film ever made. The water planet Aquarius is heading towards Earth after flooding the home planet of the warrior race of the Dinguil. The Dinguil use warp technology to make the planet move towards Earth faster than usual. The warrior race plans to flood Earth and make it their new home. When Earth learns of this, they make plans to evacuate humanity. Unfortunately, the Dinguil destroy the evacuation fleets. The space battleship Yamato, under the newly revived Jyuzo Okita (who seemingly died in the first season of the original series) now has to fight the Dinguil and stop Aquarius from flooding the Earth.

The story of CC2 centers around an investigative journalist named Stanley Mouse, who wants to find out about the legend of an ancient "cat tribe" lost in Africa. He finds them and much more, once again threatening the continued existence of mouse civilization. Special Agent Grabowsky will act to save the day, however. The events are supposed to take place at least 10, possibly 20 years after the first episode, as one of the already leaked cells shows the titular Cat-Catcher mecha rusting away in a shelter.