Fritz the Cat may have lost one of his lives in the comics, but in his new movie, he has eight more lives left to go! While his wife screams at him, Fritz lights up a joint and reminiscences about what could have been. Fritz, now married and with a son, is desperate to escape from the domestic hell he now finds himself in. Lighting up a joint, he begins to dream about his eight other lives, hoping to find one that will provide a pleasant distraction. The drug-induced journeys he takes include spells as an astronaut, Hitler's psychiatrist, a courier travelling in hostile territory during a race war, and as a pupil of an Indian guru living in the sewers of New York.

A hypocritical swinging college student cat raises hell in a satiric vision of various elements on the 1960s. A persiflage on the protest movements of the 60s. Its hero is the bold and sex-obsessed tom-cat Fritz the Cat, as created by the legendary underground artist Robert Crumb. Quitting university Fritz the Cat wanders through the hash, Black Panther and Hell's Angels scenes to find to himself.