A malfunction threatens to destroy Stitch and his friendship with Lilo! Taking place between the original "Lilo and Stitch" and "Stitch: The Movie", "Lilo and Stitch 2" finds the rowdy extraterrestrial getting used to life with his new ohana. However, a malfunction in the ultimate creation of Dr. Jumba soon emerges, which reinstates his destructive programming and threatens to both ruin his friendship with Lilo and to short him out for good!

Stitch, an alien living on Earth disguised as a dog with his human family, continues his adventures when he discovers that the alien family he never knew he had is now in Hawaii, being hunted down by galactic forces. All the characters of the warm and fluffy "Lilo and Stitch" are back! In "Stitch! - The Movie", Stitch, Jumba, and Peakley are all living with Lilo and Nani. But no one knows that Jumba had secretly deactivated all 625 of his other experiments and brought them with him. The ex-captain Gantu, hired by Jumba's former partner, Dr. Jacques Von Hamsterveil, goes to find them, and captures Jumba to interrogate him into telling where they are. Now, Lilo and Stitch have to save Stitch's ohana from being used for chaos. Two experiments are activated in this movie: Experiment 221, "Sparky", with the ability to cause big electric surges, and Experiment 625, who has all the abilities of Stitch, but is lazier. At least he makes good sandwiches!

A Hawaiian girl adopts an unusual pet who is actually a notorious extra-terrestrial fugitive from the law. In a place far, far away, illegal genetic experiment #626 is detected: Ruthless scientist Dr. Jumba Jookiba has created a strong, intelligent, nearly indestructible and aggressive being with only one known weakness: The high density of his body makes it impossible for the experiment to swim in water. The scientist is sentenced to jail by the Grand Council of the Galactic Federation. The experiment is supposed to be transported to a prison asteroid, yet manages to escape Captain Gantu, who was supposed to deliver him there. With a stolen police cruiser (the red one), the destructive being races towards a little and already doomed planet: Earth. Stranded on Hawaii, experiment #626 can't actually do much harm: water all around, no big cities and two well-equipped representatives of the Galactic Federation already following close behind to catch him again. But Dr. Jookiba and the Earth expert Pleakley never could have guessed that earth girl Lilo adopts the experiment as dog, gives him ...